According to Wiki: Burke worked as a model for Venus Swimwear and Frederick's of Hollywood. From 1999 to 2002, Burke became known while hosting Wild On!, a travel series on the E! Entertainment Television channel replacing previous host Jules Asner. As part of the series, she traveled the world extensively, profiling many popular travel destinations.
Burke first appeared nude during her early modeling career for the website BlueNudes, and most notably after gaining fame in the May 2001 and November 2004 issues of Playboy. She also appeared in men's magazines such as Maxim, Stuff, and FHM. In 2007, she was listed as one of Blender's hottest women of film and TV.
Burke has fronted infomercials promoting a Swiss ball video home fitness workout named Gunnar Peterson's Core Secrets, and appears in the first video of the series titled 20 Minute Full Body Workout. The infomercials have screened in New Zealand and Australia.
In 2005 and 2006, Burke hosted the CBS summer reality show Rock Star, an American Idol-like series in which aspiring singers competed to become either the frontman or frontwoman for a rock band.
She was the voice and face of "Rachel Teller" in Electronic Arts' video game Need for Speed: Underground 2, and asks the "People and Places" questions in the video game Trivial Pursuit Unhinged. Burke starred as a playable character in the Burger King advergaming title PocketBike Racer and in Big Bumpin'. Burke has also landed roles in several television commercials for Discover Card, Coca-Cola, Anheuser-Busch, and M Professional Cosmetics.
In 2007, Burke started a company called Baboosh Baby, which offers wraps for pregnant women. The company's website features a blog from Burke about her children.
In 2009, Burke hosted NBC's pre-show for the 66th Annual Golden Globe Awards with Tiki Barber and Nancy O'Dell.
Burke, along with Derek Hough as her partner, won Season 7 of Dancing with the Stars. She later went on to replace Samantha Harris as co-host of the program. Burke also starred in the TV show host edition of The Weakest Link. In August 2010, Burke will host the third season of the TV Land series She's Got the Look, a modeling competition show for women over 35.
Burke began hosting Season 10 of Dancing with the Stars alongside Tom Bergeron.